inherited traits are governed controlled by

Inherited Traits Are Governed Controlled By

Answers

Answer 1
Answer:

Inherited traits are controlled by genes. In this case, genetic material.
Answer 2
Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype.

Genetic material.

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Questions

1. What is hemophilia?

2. Is hemophilia dominant or recessive?

3. What are the chromosomes for a female?

4. What are the chromosomes for a male?

5. Which chromosome is hemophilia attached/carried on?

6. Are males or females more likely to have hemophilia?

7. What is a carrier?

8. Who can be a carrier of hemophilia?

9. Does a carrier have hemophilia?

10. What are the alleles for a carrier of hemophilia?

11. What are the alleles for a male with hemophilia?

12. What are the alleles for a male with normal blood clotting?

13. What are the alleles for a female with normal blood clotting?

14. what are the alleles for a female with hemophilia?

15. What treatments are there for hemophilia? (may need to look this one up)

Answers

1.      A genetic condition known as hemophilia affects the blood's ability to clot, leading to frequent bleeding and easy bruising.

2. Recessive genetic disorder, hemophilia

3. For a female, the chromosome number is XX.

4. A male's chromosomes are XY.

5. The X chromosome is responsible for hemophilia.

6. Hemophilia is more common in men.

7. A person who does not have a genetic disorder but has a copy of the gene for it is known as a carrier.

8. Hemophilia can be carried by anyone.

9. A carrier doesn't have hemophilia, not at all.

10. XH and Xh are the alleles for a hemophilia carrier.

11. 12. A male with hemophilia carries the alleles XhY. For a male with normal blood clotting, the alleles are XHY.

13. For a female with normal blood clotting, the alleles are XX.

14. Females with hemophilia have the alleles XHXh.

15. Replacement therapy, which involves injecting the patient with the missing clotting factor, and gene therapy, which aims to correct the genetic defect that causes the disorder, are two types of treatments for hemophilia. Symptom management options include blood transfusions and physical therapy.

What is Hemophilia?

Most of the time, hemophilia is a condition in which the blood does not clot properly. This can cause bleeding on its own or as a result of an injury or surgery. Numerous proteins known as clotting factors can assist in stopping bleeding.

Symptoms Excessive and unexplained bleeding from cuts, wounds, surgery, or dental work.

a lot of deep or large bruises.Strange bleeding following vaccinations.Joint discomfort, swelling, or tightness.Stool or urine stained with blood.bleeds to the nose with no known cause.Unidentified irritability in infants.

Hemophilia comes in three forms:

Hemophilia: The most prevalent form of hemophilia is this one...Hematuria: When you don't have enough clotting factor 9 (factor IX), you get hemophilia B...Hemophilia: Deficiency of factor 11 (factor XI) is another name for hemophilia

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Show how the alleles for tall plant height and short plant height are segregated from each other during gamete formation.

Answers

Answer:1111

Explanation:1111

The results of the crossing indicate that all of the offspring's genotypes will be Tt. Several genotypes are produced in the progeny of a species cross.

What is Crossing over?

When chromosomes belonging to the identical type are paired together during meiosis, a biological event called crossing over takes place. Components of the chromosome could be exchanged when two chromosomes, one from the mother along with the father, line up.

Several genotypes are produced in the progeny of a specie cross. The total number of genes that an organism has inherited from both of its parents is referred to as genotype.

The dominant allele is represented by the capital letter. If the trait is present in an organism, it always manifests itself regardless of whether the other allele is present. For instance, TT or Tt will be used to indicate tall plants.

The following are the ways in which species cross;

T × t = Tt

T × t = Tt

T × t = Tt

T × t = Tt

As a result, all of the offspring's genotypes will be Tt.

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Explain which part of DNA stores and transmits genetic information

Answers

Answer:

Explanation:

DNA, or deoxyribonucleic acid, is the molecule that stores and transmits genetic information in all living organisms. Genetic information is stored in the sequence of nucleotides, the building blocks of DNA. Each nucleotide is made up of a sugar, a phosphate group, and a nitrogenous base. There are four types of nitrogenous bases in DNA: adenine (A), thymine (T), guanine (G), and cytosine (C).

The specific sequence of these bases along the DNA strand is what encodes the genetic information. For example, the sequence ATGCAGA might code for a specific protein, while the sequence GACATAG might code for a different protein. These sequences of bases are stored in specific regions of the DNA called genes.

The genetic information is transmitted during cell division, when the DNA is replicated, and during protein synthesis, when the information in the DNA is used to build the specific proteins determined by the genetic code.

Beginning with the flow phase arrange the bichemical processes in the order in which they occur during the menstural cycle

Answers

Beginning with the flow phase, the biochemical processes in the order in which they occur during the menstrual cycle include the following below:

1. High progesterone levels maintain the endometrium lining of the uterus.

2. Endometrium lining breaks down and low levels of estrogen stimulate the pituitary to release FSH and LH.

3. FSH and LH stimulates the follicles to develop and the oocyte to produce estrogen.

4. Rising estrogen levels suppress FSH production and development of other follicles.

5. A spike in LH causes follicle to rupture.

6. A breakdown of corpus luteum causes progesterone level to drop.

What is Menstrual cycle?

This is referred to as the monthly series of changes a woman's body goes through in preparation for the possibility of pregnancy.

High progesterone levels maintain the endometrium lining of the uterus and undergoes several processes mentioned above till breakdown of corpus luteum causes progesterone level to drop.

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The question is:

Beginning with the flow phase arrange the biochemical processes in the order in which they occur during the menstural cycle

FSH and LH stimulate the follicles to develop and the oocyte to produce estrogen.

A breakdown of corpus luteum causes progesterone levels to drop.

A spike in LH causes the follicle to rupture.

The endometrial lining breaks down and low levels of estrogen stimulate the pituitary to release FSH and LH.

Rising estrogen levels suppress FSH production and development of other follicles.

High progesterone levels maintain the endometrial lining of the uterus.

What is a rainforest average precipitation?

Answers

A rainforest's average precipitation ranges from 200 to 1000 centimeters (80 to 400 inches) per year.

Tropical rainforests are mostly evergreen and high rainfall areas.

Rainforests are some of the oldest ecosystems on Earth, some of which have survived in their present form for at least 70 million years. Covering only 6% of the Earth's surface, it is home to more than half of the world's incredibly diverse and complex plant and animal species. Rainforest regions have an average temperature of 20 to 29 °C (68 to 84 °F), with no month falling below 18 °C (64 °F). Temperatures become critical as altitude increases. In the humid tropics, the temperature drops by about 0.5 °C (0.9 °F) for every 100 meters (328 feet) of altitude.

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which part of the eye transmits visual information to the brain?

Answers

The optic nerve sends visual information from the retina in the eye to the brain.

What is the optic nerve?

In the eye, the retina is the light-sensitive tissue at the back of the eye. Since it has photoreceptors cells named rods and cones, the retina has an ability to convert light and images, into an electrical impulse. Then the retina sends this impulse to the brain through the optic nerve.

The optic nerve, a cable-like grouping of nerve fibers connects and transmits visual information from the eye to the brain. In the brain, the optic nerve sends signals to the visual cortex where the image is converted into an object we see. Any damage of the optic nerve leads to vision distortion or vision loss.

Thus, a fully functional optic nerve is essential for vision by transmitting visual information from the eye to the brain.

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I can't really understand ocean currents

Answers

Basically the Gravity, wind (Coriolis Effect), and water density all contribute to the continuous, predictable, directed movement of seawater termed as ocean currents.

How ocean currents affect weather patterns?

Ocean currents affect weather patterns by;

bringing cold water from the poles back to the tropics and warm water and precipitation from the equator toward the poles. As a result of above, currents control the climate globally, also helping to balance out the uneven distribution of solar radiation that reaches the surface of the Earth.

Features of ocean currents:Water in the ocean because of above mentioned factors can move both horizontally and vertically. Vertical shifts are  usually referred to as upwellings or downwellings, while horizontal motions are known as currents.

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Select the correct answer.
Flagellates are microbes that have a rod-shaped flagellum that helps with their locomotion. Certain flagellates reside inside termites. These flagellates provide enzymes for the termites to digest cellulose, which helps them survive. In turn, the termites provide nourishment to these flagellates. Termites need cellulose for their survival, and flagellates obtain nutrition only from termites. Which statement can be true about the association between these microbes and termites?
A.
The flagellates share a facultative mutualistic association with the termites.
B.
The flagellates and termites share an obligate mutualistic association.
C.
The flagellates share an obligate parasitic association with the termites.
D.
The flagellates and termites share a commensal association.
E.
The flagellates and termites share a facultative parasitic association.

Answers

B. The flagellates and termites share an obligate mutualistic association.

Are there specific flagellates that live within termites that have a rod-shaped flagellum that aids in their motility in microbes?

Microbes known as flagellates have a flagellum, which is fashioned like a rod and is used for propulsion. Several flagellates are housed within termites. The termites can digest cellulose using these flagellates' enzymes, which aids in their survival. These flagellates in turn receive food from the termites.

Which of the following statements concerning the relationship between bacteria and termites can be true?

Mutualism describes the interaction between termites and bacteria since both species gain from it.

What kind of movement do flagellates engage in?

Flagellar locomotion can take the form of three-dimensional waves, oar-like beating, or planar waves. Contraction waves pass from the base to the tip of the flagellum or in the opposite direction to cause forward or backward movement in all three of these types of flagellar locomotion.

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PLSSS HELP IF YOU TURLY KNOW THISS

Answers

Answer:

Organisms

Explanation:

Water, Minerals, and Air are the resources while Organisms are the ones that fight for those resources

Buying organically grown foods supports sustainability.
a) True
b) False

Answers

The answer to your question is true.

MULTIPLE CHOICE
When does flowing water deposit the sediments it is carrying?
A
B
C
D
when the water current slows down
when the water current speeds up
only when the river changes direction
water does not deposit sediments, it only erodes sediments

Answers

Answer: A. when the water current slows down.

Explanation:

When a water current slows down, the force of the water is not strong enough to continue carrying the sediment, so it drops the sediment and deposit it. The slower the flow, the larger the particles that can be carried and eventually deposited. This is why river deltas, for example, are formed where a river enters a body of water and the flow slows down, allowing sediment to build up and create landforms.

12. Explain how reducing the amount of soda you drink could reduce the amount of fossil fuels that are consumed as well as the amount of aluminum that is consumed.

Answers

Answer:

Reducing the amount of soda you drink can reduce the number of fossil fuels consumed in several ways. First, the production of soda requires energy to power the manufacturing facilities and transport the finished product to stores and distributors. By drinking less soda, there is less demand for these energy-intensive processes.

Second, soda is often packaged in aluminum cans or bottles. The production of aluminum also requires a significant amount of energy, so reducing the amount of soda consumed can also reduce the amount of aluminum produced. Additionally, recycling aluminum cans and bottles also requires a significant amount of energy, so reducing the amount of soda you drink can also reduce the amount of energy needed to recycle aluminum.

Explanation:

Calculate the total number of Guinea pig offspring. Write this total at the bottom of the table. What percentage of the total number of Guinea pigs has short hair? What percentage of the total number of Guinea pigs has long hair?

Answers

Percentage of Guinea pigs with long hair overall and a 50% likelihood of having offspring having brown fur

What happened to Offspring?

One of the Partner's cofounders, played bass for the group up until 2018, after being expelled over a business disagreement, leaving Holland even as lone surviving original member

Why Offspring's cancellation?

John Edwards announced on October 3 that Offspring would not be back for a sixth season owing to cost-cutting measures taken by Ten inside its production division. This announcement came shortly after fifth series finale aired.

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There were _____ people in 1960.

Answers

Answer:  3,034,949,748

Explanation: If u do some research on the web you could find the answer.

Help me please I need this soon

Answers

Answer:

In teliphase four daughters are formed

Answer of 20 is yes

Is the following statement true or false?
All cells have the same DNA, but different types of cells express different sets of genes.

Answers

The leading cause of lung cancer risk is cigarette smoking. About 80% to 90% of lung cancer deaths in the US are attributed to smoking cigarettes.

Smoking cigars and pipes as well as other tobacco products raises the risk of developing lung cancer.

What are the two cancers brought on by a change in lifestyle?

Diet - The usual foods you choose to eat can potentially increase your risk of getting certain cancers. A diet high in processed meats, such as ham, bacon, or salami, can raise your risk of stomach cancer, bowel cancer, and pancreatic cancer.

How may one's way of life be changed to treat lung cancer?

You can manage the side effects of cancer and its treatment with the support of a healthy diet, exercise, and stress-relieving activities. In fact, according to Dr. Yarmus, some cancer treatments are more effective when you exercise more, eat healthier, and eliminate bad habits like smoking.

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What is the function of spindle fibers? Where do they attach?

Answers

During prophase of mitosis, a specialized region on the centromere called the kinetochore attaches the chromosomes to the spindle filaments.

A centromere is the part of the chromosome that connects sister chromatids. During mitosis, spindle fibers attach to centromeres via kinetochores. Kinetochores produce kinetochore fibers that attach sister chromatids to spindle filaments. Kinetochore and polar spindle fibers work together to manipulate and segregate chromosomes during mitosis and meiosis.

Spindles form protein structures that divide the genetic material within the cell. The mitotic spindle is required to evenly divide the parent cell's chromosomes into her two daughter cells in both types of nuclear division.

mitosis and meiosis.

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Which of the following describes a holocrine gland?

Answers

Sebaceous gland can be categorized as a holocrine gland.

An endocrine gland is a gland which does not use any duct and releases all its secretions directly into the blood. For example, pituitary gland, thyroid gland. An exocrine gland can be defined as the gland which uses a duct system secretes its secretions. Some examples of exocrine glands are the mammary glands, salivary glands etc.

Holocrine glands can be defined as those glands whose secretions are produced in the cell cytoplasm and are released into the lumen as a result of the rupture of the plasma membrane. Sebaceous gland is categorized as a holocrine gland.

--The given question is incomplete, the complete question is

"Which of the following describes a holocrine gland? a. Pancreas b. Testis c. Sebaceous d. None of the above."--

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For the ipledge program, male latex condoms can be used with or without a spermicide.a. Trueb. False

Answers

All participants in this programme who have the potential to get pregnant must fully commit to preventing pregnancy.

It is true

Whether or not to use spermicide when using male latex condoms?

The only birth control methods that also aid in STI prevention are external (male) and internal (female) condoms. Either one can be used alone or in conjunction with other birth control methods like spermicide.

What prerequisite does the iPLEDGE programme have?

iPLEDGE asks you to consent to using two types of birth control if it is physiologically possible for you to get pregnant. No of your amount of sexual activity, sexual orientation, or gender identity, this is typically necessary.

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what is the role of cholesterol in a phospholipid bilayer

Answers

Answer:

Cholesterol plays a very significant role in the phospholipid bilayer.

Explanation:

It increases the order of the lipid packing, lowers the membrane permeability, and maintains membrane fluidity by forming liquid-ordered–phase lipid rafts

What type of inheritance is shown by the genes that control sickle cell anemia? Explain your response.

Answers

Answer:

This condition is inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

how is our atmosphere different from the atmosphere on venus and mars

Answers

Answer:

Earth's atmosphere is a mixture of nitrogen (79%), oxygen (20%), and a small fraction of carbon dioxide, water vapours and other gases. This makes the existence of life possible on Earth. However, the atmospheres on Venus and Mars mainly consist of carbon dioxide.

90 % of marine organisms and 70% of land organisms died off due to environmental and/or climate changes during the paleozoic era.

Answers

During the Paleozoic era, marine organisms and land organisms died due to environmental changes such as warmer temperatures and drier soil.

What is the paleozoic era?

The Paleozoic era is the time when the Earth's condition was still unstable. This epoch lasted about 340 million years. Signs of life such as single-celled creatures (microorganisms), small animals without backbones, types of fish, and types of algae or grasses began to be found.

Natural conditions that began to change with warm temperatures and drier soil caused marine and land organisms to die so the Mesozoic era was also referred to as the age of reptiles because the earth was dominated by large reptiles such as dinosaurs and Atlantosaurus.

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What are 3 types of prey defense?

Answers

The three types of prey defense are physical, chemical and behavioral defense.

Predators are the animals which obtain their nutrition by killing and eating other animals while prey are the animals that get killed or hunted by the predators.

Preys need certain mechanisms to defend themselves and these mechanisms can be either physical, chemical or behavioral. Physical defense include protective shells, or thorns on the body which helps them keep their predator away. Chemical defense include production of certain chemicals or odors which keep their predators away from them and behavioral defense includes speed to flee from the predator, camouflage to blend in with the environment etc.

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What are some functions of cells produced from mitosis?

The cells will be identical and can be used for growth and tissue repair.
The cells will be genetically diverse for asexual reproduction.
The cells will contain some DNA from the parent cell for tissue repair.
The cells will contain a partial genome from the parent cell for sexual reproduction.

Answers

Answer:

A:  The cells will be genetically identical to the parent cell and can be used for growth and tissue repair.

Explanation:

Which of the following forms of homeostasis would not be affected by a severe burn involving both the epidermis and dermis

Answers

Answer:

loose connective tissue.

Explanation:

Which of the following forms of homeostasis would not be affected by a severe burn involving both the epidermis and dermis? loose connective tissue.

Write a paragraph discussing how producers can use information on optimal growth ranges of plants in their crop selection and production practices. address water, light,temperature, PH, and nutrients in your discussion.

Answers

Abiotic resources such as water, light, temperature, PH, and nutrients affect the optimal growth ranges of plants and therefore they should be considered during breeding programs for crop selection and production.

What is the relative importance of abiotic resources in crop production?

The abiotic resources are fundamental in any type of crop production and therefore different non-living factors which include water, light, temperature, PH, and nutrients must be taken into account in breeding programs.

Therefore, with this data, we can see that water, light, temperature, PH, and nutrients are factors that should be considered during the improvement of a crop.

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Which of these is characteristic of the photic zone of a freshwater biome?
A)the presence of algae
B)relatively cool water
C)relatively stable water temperature
D)dead organic matter
E)low oxygen level

Answers

These is characteristic of the photic zone of a freshwater biome are the presence of algae as Algae are found in all types of water, including salt water, fresh water, and brackish water (a mixture of salt and fresh water). Algae that live in water are divided into two types: algae and phytoplankton.

Algae are large plants made up of many cells, while phytoplankton are small single-celled plants. Photosynthetic algae called phytoplankton live in the photozone. Zooplankton - small free-floating animals - feed on phytoplankton.

This is the first step in many aquatic food webs. Below the light zone is a dark non-light zone where photosynthesis is not possible. Freshwater benthic algae are found in the photozones of streams and rivers, lakes, and wetlands. A number of terms are used to distinguish groups of benthic organisms that live in various aquatic habitats.

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Which of the following best describes the shape of the sampling distribution of the sample proportion?a. When standardized, it is exactly the standard normal distribution.b. When standardized, it is the t distribution.c. It is approximately normal as long as n is greater than or equal to 30.d. It is approximately normal as long as np is greater than or equal to 10 and n(1-p) is greater than or equal to 10.e. None of these are correct.

Answers

Option d is Correct. As long as np is greater than or equal to 10 and n(1-p) is greater than or equal to 10, it is about normal.

The population proportion is the mean of all sample proportions (p-hat) when repeated random samples of a given size n are collected from a population of values for a categorical variable, where the proportion in the category of interest is p. (p).

The sample mean distribution is centered on the population mean and has a heap shape, similar to the normal distribution. Even when the underlying data is NOT normally distributed, the sample means are NORMALLY distributed if the sample size is 30 or above!

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Correct Question:

Which of the following best describes the shape of the sampling distribution of the sample proportion?

a. When standardized, it is exactly the standard normal distribution.

b. When standardized, it is the t distribution.

c. It is approximately normal as long as n is greater than or equal to 30.

d. It is approximately normal as long as np is greater than or equal to 10 and n(1-p) is greater than or equal to 10.

e. None of these are correct.

Which term would be directly related to the science of ecology? Select all that apply.
Responses


endocrine system

integumentary system


population density


population growth

Answers

Answer: population desnsity

Explanation: Types, Importance And Examples Of Ecology What is Ecology? Ecology is a branch of science, including human science, population, community, ecosystem and biosphere. Ecology is the study of organisms, the environment and how the organisms interact with each other and their environment.

Answer:

population density

population growth

Explanation:

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Which of the following is not true regarding the radulae of a snail? View Available Hint(s) They are used in conjunction with fungal spores also deposited by the snails. They are used as the snails crawl along the leaf surface. They are used to prepare leaves for fungal growth. They scrape, but do not wound, the leaf tissue. They form a band of saw-like teeth. a Submit In the renal corpuscle, increasing the pressure in the capsular space (intracapsular pressure) will result in:A. The filtrate becoming more concentrated, in other words the osmolality would increase in the filtrateB. Glomerular filtration rate rate would increaseC. Glomerular filtration rate would decreaseD. Increasing the pressure in the capsular space would not effect GFR or filtrate osmolality File encryption protects data on a computer against the following except:A. Trojan cryptoB. hostile usersC. theftD. Trojans Consider the following abbreviated financial statements for Parrothead Enterprises: 2020 2021 PARROTHEAD ENTERPRISES 2020 and 2021 Partial Balance Sheets Assets 2020 2021 Liabilities and Owners' Equity $ $ Current assets Current liabilities 1,302 1,435 Net fixed assets 5,085 6,164 Long-term debt $ 594 $ 637 2,804 2.987 PARROTHEAD ENTERPRISES 2021 Income Statement $ Sales 16,066 Costs 7,279 Depreciation 1,459 Interest paid 452 a. What is owners' equity for 2020 and 2021? (Do not round intermediate calculations.) b. What is the change in net working capital for 2021? (Do not round intermediate calculations.) C-1. In 2021, Parrothead Enterprises purchased $2,688 in new fixed assets. How much in fixed assets did Parrothead Enterprises sell? (Do not round intermediate calculations.) c-2. In 2021, Parrothead Enterprises purchased $2,688 in new fixed assets. What is the cash flow from assets for the year? The tax rate is 24 percent. (Do not round intermediate calculations.) d-1. During 2021, Parrothead Enterprises raised $584 in new long-term debt. How much long-term debt must Parrothead Enterprises have paid off during the year? (Do not round intermediate calculations.) d-2. During 2021, Parrothead Enterprises raised $584 in new long-term debt. What is the cash flow to creditors? (Do not round intermediate calculations.) a. Owners' equity 2020 a. Owners' equity 2021 b. Change in NWC C-1. Fixed assets sold c-2. Cash flow from assets d-1. Debt retired d-2. Cash flow to creditors if the focus of change is a relatively small work group, diagnosis of the problem may be best accomplished through _________. A process has a flow rate of 12 units per day, and a throughput time of 1 day. Applying Little's Law, how much inventory will be in the process? 37 units O 12 units O 300 units O Approximately 2 units -2x - 6x =15Atenderes form A sample size that is one-fourth the original size causes the margin of error to quarter halve double quadruple remain unchanged the receiver of a parabolic satellite dish is at the focus of the parabola (see figure). write an equation for a cross section of the satellite dish. what is the relation between the number of transmit antennas and the number of receive antennas for spatial multiplexing to be possible. provide a mathematical argument for your answer. fill in the blank. currently, about _____ percent of the worlds heads of government are men. a. true b. false : a photon must have exactly the right energy to excite an electron from one energy level to another energy level. though treatment is known to work, there is no definitive answer as to which treatment works best.True or False how does shakespeare highlight the theme of love and fate through the imagery between romeo and juliet Can some one help me with it Estimate the equilibrium composition at 400K and 1 atm of the following gaseous reactions:n C Hi 2(g) iso-C H12(g) & n-C H12(g) neo-C H12(g), Standard Gibbs energy of formation data for n-pentane (1), isopentane (2), and neopentane (3) at 400K are 40.195, 34.413, and 37.640 kJ/mol, respectively. Assume ideal-gas behavior. radiographers should wear their dosimeter facing forward at the collar-level to approximate their radiation dose to the 1. thyroid gland 2. gonads 3. breasts A problem with the classical theory for radiation from a blackbody was that the theory predicted too much radiation in the ________________ wavelengths.a. visibleb. ultravioletc. infraredd. radioe. microwave coil is a large turn circular coil of radius . circular coil has turns, a radius of and is located from coil along the same axis. the planes of the two coils are parallel. If the current in coil A varies with time according to I = 16*t^3 - 90*t^2 - 1, where I is in amps and t is in s, find the magnitude of the EMF induced in coil B at time t = 5.0. So part one of the question asked for the mutual inductance which i calculated as 7.37E-4 H Im confused how to use the mutual inductance to calculate the emf in coil B how do we know that eukaryotic transcription factors bind to dna sequences at or near promoter regions?